{"id":1400,"date":"2020-05-12T02:32:04","date_gmt":"2020-05-12T02:32:04","guid":{"rendered":"http:\/\/caninemegaesophagusinfo.com\/staging\/?page_id=1400"},"modified":"2026-08-23T16:18:45","modified_gmt":"2026-08-23T16:18:45","slug":"research","status":"publish","type":"page","link":"https:\/\/caninemegaesophagusinfo.com\/index.php\/research\/","title":{"rendered":"Research &#038; Studies"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_section][vc_row content_placement=&#8221;middle&#8221;][vc_column width=&#8221;1\/6&#8243;][vc_single_image image=&#8221;1518&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column][vc_column width=&#8221;5\/6&#8243;][vc_row_inner][vc_column_inner width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;1538&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][vc_empty_space height=&#8221;16px&#8221;][vc_single_image image=&#8221;1535&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;3\/4&#8243;][vc_column_text]<\/p>\n<h4>Washington State University<\/h4>\n<p>[\/vc_column_text][vc_column_text]<\/p>\n<div><em>Under the direction of Assistant Professor Dr. Jillian Haines<\/em><\/div>\n<p><a href=\"https:\/\/labs.wsu.edu\/megaesophagus\/\" target=\"_blank\" rel=\"noopener\"><strong>https:\/\/labs.wsu.edu\/megaesophagus\/<\/strong><\/a><br \/>\n[\/vc_column_text][vc_empty_space height=&#8221;16px&#8221;][vc_separator][vc_empty_space height=&#8221;16px&#8221;][vc_column_text]<\/p>\n<ul>\n<li><a href=\"https:\/\/caninemegaesophagusinfo.com\/wp-content\/uploads\/2022\/07\/Screenshot_20220728-113320_Drive.jpg\">Gastroesophageal sphincter changes<\/a> in dogs with Megaesophagus for owners<\/li>\n<li><a href=\"https:\/\/caninemegaesophagusinfo.com\/wp-content\/uploads\/2022\/07\/Screenshot_20220728-113347_Drive.jpg\" target=\"_blank\" rel=\"noopener noreferrer\">Gastroesophageal sphincter changes<\/a> in dog with Megaesophagus for veterinarians<\/li>\n<li><a href=\"https:\/\/caninemegaesophagusinfo.com\/staging\/wp-content\/uploads\/2020\/05\/Jillian-Haines-Technique-for-Evaluation.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Technique for Evaluation<\/a> of Gravity-Assisted Esophageal Transit Characteristics in Dogs with Megaesophagus<\/li>\n<li style=\"text-align: left;\">\u00a0<a href=\"https:\/\/avmajournals.avma.org\/view\/journals\/ajvr\/aop\/ajvr.21.02.0030\/ajvr.21.02.0030.xml?tab_body=fulltext\" target=\"_blank\" rel=\"noopener noreferrer\">Clinical Study <\/a>Efficacy of liquid Sildenafil as a novel treatment for canine generalized megaesophagus: <a href=\"https:\/\/caninemegaesophagusinfo.com\/wp-content\/uploads\/2022\/03\/American-Journal-of-Veterinary-Research-A-randomized-crossover-study-of-compounded-liquid-sildenafil-for-treatment-of-generalized-megaesophagus-in-dogs-1-1.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">A randomized crossover study<\/a><\/li>\n<li><a href=\"https:\/\/news.wsu.edu\/press-release\/2022\/02\/21\/viagra-promising-as-treatment-for-dogs-with-often-fatal-eating-disorder\/\">Viagra promising as treatment for canine eating disorder<\/a><\/li>\n<li><a href=\"https:\/\/www.purinaproclub.com\/dog-articles\/health\/great-dane-megaesophagus\">Great Dane Puppies With Megaesophagus May Benefit from New Treatment<\/a><\/li>\n<li><a href=\"https:\/\/caninemegaesophagusinfo.com\/staging\/wp-content\/uploads\/2020\/05\/Jillian-Haines-Survey-paper.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Survey of owners<\/a> on population characteristics, diagnosis, and environmental, health, and disease associations in dogs with megaesophagus<\/li>\n<li>Kyla undergoing <a href=\"https:\/\/www.facebook.com\/rescue4all\/videos\/1089133157835064\/\">Video Fluoroscopy<\/a> while eating in her bailey chair<\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_empty_space height=&#8221;50px&#8221;][\/vc_column][\/vc_row][vc_row][vc_column][vc_empty_space][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/6&#8243;][vc_single_image image=&#8221;1865&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column][vc_column width=&#8221;5\/6&#8243;][vc_column_text]<\/p>\n<h4><b>University of Cambridge<\/b><\/h4>\n<p>[\/vc_column_text][vc_column_text]<em>Under the Direction of An Vanhaesebrouck, DVM<\/em>[\/vc_column_text][vc_empty_space height=&#8221;16px&#8221;][vc_separator][vc_empty_space height=&#8221;16px&#8221;][vc_column_text]<\/p>\n<ul>\n<li><span style=\"font-family: arial, sans-serif;\"><a href=\"https:\/\/caninemegaesophagusinfo.com\/wp-content\/uploads\/2023\/12\/Project-myasthenia-Cambridge_Donna.pdf\">Search for antibodies in &#8216;Seronegative&#8217; myasthenia gravis in dogs &#8211; <strong>Clinical Study<\/strong><\/a><\/span><\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_empty_space height=&#8221;50px&#8221;][\/vc_column][\/vc_row][vc_row][vc_column][vc_empty_space][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/6&#8243;][vc_single_image image=&#8221;1521&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column][vc_column width=&#8221;5\/6&#8243;][vc_column_text]<\/p>\n<h4><b>Missouri College of Veterinary Medicine<\/b><\/h4>\n<p>[\/vc_column_text][vc_column_text]<em>Under the Direction of Carol Reinero DVM, PhD<\/em>[\/vc_column_text][vc_empty_space height=&#8221;16px&#8221;][vc_separator][vc_empty_space height=&#8221;16px&#8221;][vc_column_text]<\/p>\n<ul>\n<li><span style=\"font-family: arial, sans-serif;\">The Veterinary Health Center (VHC) at the University of Missouri\u2019s College of Veterinary Medicine have identified\u00a0an\u201dLES-achalasia-like syndrome\u201d in some dogs with idiopathic megaesophagus and have come up with a\u00a0<a href=\"http:\/\/m.phys.org\/news\/2016-10-team-treatment-canine-megaesophagus.html\" target=\"_blank\" rel=\"noopener noreferrer\">treatment plan.<\/a>\u00a0<\/span><\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_empty_space height=&#8221;50px&#8221;][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/6&#8243;][vc_single_image image=&#8221;1871&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column][vc_column width=&#8221;5\/6&#8243;][vc_column_text]<em>Under the Direction of Aida I. Vient\u00f3s-Plotts, DVM, PhD, DACVIM<\/em>[\/vc_column_text][vc_empty_space height=&#8221;16px&#8221;][vc_separator][vc_empty_space height=&#8221;16px&#8221;][vc_column_text]<\/p>\n<ul>\n<li>The main goal of the <a href=\"https:\/\/vhc.missouri.edu\/small-animal-hospital\/small-animal-internal-medicine\/breathe-clinic\/\">BREATHE Clinic<\/a> is to provide a comprehensive evaluation of dogs and cats with respiratory and swallowing disorders to allow individualized management. A secondary goal is to learn more ways to help canine and feline patients by conducting clinical research. <a href=\"https:\/\/vhc.missouri.edu\/small-animal-hospital\/small-animal-internal-medicine\/breathe-clinic\/\" target=\"_blank\" rel=\"noopener noreferrer\">Click for more information about The BREATHE Clinic<\/a><\/li>\n<li dir=\"ltr\"><a href=\"https:\/\/www.veterinariansforpr.org\/\" target=\"_blank\" rel=\"noopener noreferrer\">Click for more information about Veterinarians for Puerto Rico<\/a><\/li>\n<li dir=\"ltr\"><a href=\"https:\/\/caninemegaesophagusinfo.com\/wp-content\/uploads\/2023\/12\/Veterinary-Surgery-2022-Winston-Management-and-outcomes-of-13-dogs-treated-with-a-modified-Heller-myotomy-and-Dor.pdf\">Clinical Study<\/a>: Management and outcomes of 13 dogs treated with a modified Heller myotomy and Dor fundoplication for lower esophageal sphincter achalasia-like syndrome<\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_empty_space height=&#8221;50px&#8221;][\/vc_column][\/vc_row][vc_row][vc_column][vc_empty_space][\/vc_column][\/vc_row][vc_row][vc_column][vc_empty_space][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/6&#8243;][vc_single_image image=&#8221;1530&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column][vc_column width=&#8221;5\/6&#8243;][vc_row_inner][vc_column_inner][vc_column_text]<\/p>\n<h4><span style=\"color: #000000;\">Clemson University &#8211;\u00a0<\/span><span style=\"color: #000000;\">Genetics and Biochemistry<\/span><\/h4>\n<p>[\/vc_column_text][vc_column_text]<em>Under the Direction of Leigh Anne Clark PhD Associate Professor<\/em>[\/vc_column_text][vc_empty_space height=&#8221;16px&#8221;][vc_separator][vc_empty_space height=&#8221;16px&#8221;][vc_column_text]<\/p>\n<ul>\n<li>\n<p class=\"entry-title\"><a href=\"https:\/\/news.clemson.edu\/researchers-discover-genetic-cause-of-sometimes-deadly-esophageal-disorder-in-dogs\/\">Researchers discover genetic cause of sometimes deadly esophageal disorder in dogs<\/a><\/p>\n<\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_column_text]<\/p>\n<ul>\n<li><a href=\"https:\/\/www.clemson.edu\/science\/departments\/genetics-biochemistry\/people\/profiles\/lclark4\" target=\"_blank\" rel=\"noopener noreferrer\">Study of Congenital Idiopathic Megaesophagus<\/a> in the German Shepherd dog and Great Dane for genetic testing.<\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_empty_space height=&#8221;50px&#8221;][\/vc_column][\/vc_row][vc_row][vc_column][vc_empty_space][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/6&#8243;][vc_single_image image=&#8221;1531&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column][vc_column width=&#8221;5\/6&#8243;][vc_column_text]<\/p>\n<h4><b>University of Pennsylvania &#8211; PennVet<\/b><\/h4>\n<p>[\/vc_column_text][vc_column_text]<em>Under the Direction of Dr. Oliver Garden, Professor BS, BVETMED, PhD<\/em>[\/vc_column_text][vc_empty_space height=&#8221;16px&#8221;][vc_separator][vc_empty_space height=&#8221;16px&#8221;][vc_column_text]<\/p>\n<ul>\n<li><a href=\"https:\/\/www.vet.upenn.edu\/research\/clinical-trials-vcic\/all-clinical-trials\/clinical-trial\/myasthenia-gravis---determination-of-pathological-autoantibodies-in-dogs-and-cats-with-myasthenia-gravis\" target=\"_blank\" rel=\"noopener noreferrer\">Myasthenia Gravis<\/a> &#8211; Determination of pathological auto antibodies in dogs. Completed. Study is closed.<\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_column_text]<\/p>\n<ul>\n<li class=\"content-title\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8478050\/?fbclid=IwZXh0bgNhZW0CMTEAAR0mfh3QDVFdOcoyd28wVESNVSDggpnL4eIVCMSG_xQJwzyeQltEdGgAxmI_aem_AWmEiUkT-K5T1qD_e1qOCUA9vkoSRktRHVSm6lAUFVLbmHwr3Y2sBu0BZlFsgT1B01jQz0kXI8MFHEfaZ_zeuNnz\">Clinical features and outcome of acquired myasthenia gravis in 94 dogs<\/a><\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_empty_space height=&#8221;50px&#8221;][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/6&#8243;][vc_single_image image=&#8221;1991&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; css=&#8221;&#8221;][\/vc_column][vc_column width=&#8221;5\/6&#8243;][vc_column_text css=&#8221;&#8221;]<em>Under the Direction of Dr. Margret L. Casal, DVM, PhD, DECAR, Professor of Medical Genetics, Reproduction, and Pediatrics<\/em>[\/vc_column_text][vc_empty_space height=&#8221;16px&#8221;][vc_separator][vc_empty_space height=&#8221;16px&#8221;][vc_column_text css=&#8221;&#8221;]<\/p>\n<div>\n<ul>\n<li dir=\"ltr\">Congenital Myasthenic Syndrome in Sealyham Terriers<\/li>\n<\/ul>\n<\/div>\n<p>[\/vc_column_text][vc_empty_space height=&#8221;50px&#8221;][\/vc_column][\/vc_row][vc_row][vc_column][vc_empty_space][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/6&#8243;][vc_single_image image=&#8221;1526&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column][vc_column width=&#8221;5\/6&#8243;][vc_column_text]<\/p>\n<h4>University of\u00a0California &#8211; Davis\u00a0Veterinary Medicine<\/h4>\n<p>[\/vc_column_text][vc_column_text]<em>Under the Direction of Dr. Stanley Marks, Professor<\/em>[\/vc_column_text][vc_empty_space height=&#8221;16px&#8221;][vc_separator][vc_empty_space height=&#8221;16px&#8221;][vc_column_text]<\/p>\n<ul>\n<li><a href=\"https:\/\/studypages.com\/s\/assessing-and-managing-megaesophagus-in-dogs-646462\/?fbclid=IwAR0av6taaQ4E5p8fxrpcTFShYpbnvUUltqwWRkSyE9M7EuMDFh8pBlfWIfs\" target=\"_blank\" rel=\"noopener noreferrer\">Assessing and Managing Megaesophagus<\/a> in Dogs<\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_empty_space height=&#8221;50px&#8221;][\/vc_column][\/vc_row][vc_row][vc_column][vc_empty_space][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/6&#8243;][vc_single_image image=&#8221;1528&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column][vc_column width=&#8221;5\/6&#8243;][vc_column_text]<\/p>\n<h4>University of\u00a0California &#8211; Davis\u00a0Veterinary Medicine<\/h4>\n<p>[\/vc_column_text][vc_column_text]<\/p>\n<div><em>Under the Direction of\u00a0Dr. Peter Dickinson, Professor<\/em><\/div>\n<p>[\/vc_column_text][vc_empty_space height=&#8221;16px&#8221;][vc_separator][vc_empty_space height=&#8221;16px&#8221;][vc_column_text]<\/p>\n<ul>\n<li><a href=\"https:\/\/studypages.com\/s\/assessing-a-stem-cell-treatment-for-myasthenia-gravis-mg-in-dogs-800053\/?ref=gallery\" target=\"_blank\" rel=\"noopener noreferrer\">Assessing a Stem Cell Treatment<\/a> for Myasthenia Gravis in Dogs (Study is closed)<\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_empty_space height=&#8221;50px&#8221;][\/vc_column][\/vc_row][\/vc_section][vc_row][vc_column][vc_empty_space][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/6&#8243;][vc_single_image image=&#8221;1686&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column][vc_column width=&#8221;5\/6&#8243;][vc_column_text]<\/p>\n<h4>University of\u00a0Missouri &#8211; College of Veterinary Medicine<\/h4>\n<p>[\/vc_column_text][vc_column_text]<em>Under the Direction of\u00a0C. R. Reinero, Professor<\/em>[\/vc_column_text][vc_empty_space height=&#8221;16px&#8221;][vc_separator][vc_empty_space height=&#8221;16px&#8221;][vc_column_text]<\/p>\n<ul>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30968469\/\" target=\"_blank\" rel=\"noopener noreferrer\">Mechanical Dilation<\/a> botulinum toxin A injection, and surgicalmyotomy with fundoplication for treatment of lower esophageal sphincter achalasia-like syndrome in dogs<\/li>\n<li>\n<p class=\"heading-title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31381208\/\" target=\"_blank\" rel=\"noopener noreferrer\">Videofluoroscopic swallow study<\/a> features of lower esophageal sphincter achalasia-like syndrome in dogs<\/p>\n<\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_empty_space height=&#8221;50px&#8221;][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_section][vc_row content_placement=&#8221;middle&#8221;][vc_column width=&#8221;1\/6&#8243;][vc_single_image image=&#8221;1518&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column][vc_column width=&#8221;5\/6&#8243;][vc_row_inner][vc_column_inner width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;1538&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][vc_empty_space height=&#8221;16px&#8221;][vc_single_image image=&#8221;1535&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;3\/4&#8243;][vc_column_text] Washington State University [\/vc_column_text][vc_column_text] Under the direction of Assistant Professor Dr. Jillian Haines https:\/\/labs.wsu.edu\/megaesophagus\/ [\/vc_column_text][vc_empty_space height=&#8221;16px&#8221;][vc_separator][vc_empty_space height=&#8221;16px&#8221;][vc_column_text] Gastroesophageal sphincter changes in dogs with Megaesophagus for owners Gastroesophageal sphincter changes in dog with Megaesophagus for veterinarians Technique for Evaluation of [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"footnotes":""},"class_list":["post-1400","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/caninemegaesophagusinfo.com\/index.php\/wp-json\/wp\/v2\/pages\/1400","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/caninemegaesophagusinfo.com\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/caninemegaesophagusinfo.com\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/caninemegaesophagusinfo.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/caninemegaesophagusinfo.com\/index.php\/wp-json\/wp\/v2\/comments?post=1400"}],"version-history":[{"count":83,"href":"https:\/\/caninemegaesophagusinfo.com\/index.php\/wp-json\/wp\/v2\/pages\/1400\/revisions"}],"predecessor-version":[{"id":1993,"href":"https:\/\/caninemegaesophagusinfo.com\/index.php\/wp-json\/wp\/v2\/pages\/1400\/revisions\/1993"}],"wp:attachment":[{"href":"https:\/\/caninemegaesophagusinfo.com\/index.php\/wp-json\/wp\/v2\/media?parent=1400"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}